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Research Publications

May 26, 2022

 

Manuscripts 

  1. Fawzia Bardag-Gorce, Michael Di Lorenzo, Robert Niihara, Sarah Sunada, Amanda Laporte, Kavita Narwani, Daileen Cortez, Jeremy Stark, Mynor Garcia, Alissa Diaz, Joan Oliva, Richard Hoft, and Yutaka Niihara. Proteasome and autophagy pathway in corneal epithelial cells with limbal stem cell deficiency.  Int J Ophthalmol Clin Res 2020, 7:112.  Volume 7 | Issue 1.  doi: 10.23937/2378-346X/1410112 
  1. Oliva J, Florentino A, Bardag-Gorce F, Niihara Y. Vitrification and storage of oral mucosa epithelial cell sheets.  J Tissue Eng Regen Med. 2019 Apr 9. doi: 10.1002/term.2864.  PMID: 30964962 
  1. Oliva J, Florentino A, Bardag-Gorce F, Niihara Y. Engineering, differentiation and harvesting of human adipose-derived stem cell multilayer cell sheets.  Regen Med. 2019 Mar;14(3):151-163. doi: 10.2217/rme-2018-0053.  PMID: 30829557.  
  1. Fawzia Bardag-Gorce , Andrew Makalinao, Imara Meepe, Richard H. Hoft, Daileen Cortez, Joan Oliva, Amanda Laporte, Jeremy Stark, Amber M. Gorce, Michael Di Lorenzo, Samuel W. French, William Lungo, Yutaka Niihara. Corneal keratin aggresome (CKAGG) formation and clearance by proteasome activation.  2018 Dec 8;4(12):e01012. doi: 10.1016/j.heliyon.2018.e01012.  PMID: 30619956 
  1. Oliva J, Ochiai K, Florentino A, Bardag-Gorce F, Wood A, Niihara Y. Feeder Cells Free Rabbit Oral Mucosa Epithelial Cell Sheet Engineering.  Tissue Eng Regen Med. 2018 Jan 16; 15(3):321-332. doi: 10.1007/s13770-017-0108-4. 
  1. Fawzia Bardag-Gorce, Richard H. Hoft, Imara Meepe, Julio Garcia, Kumar Tiger, Andrew Wood, Amanda Laporte, Derek Pan, Andrew Makalinao, Robert Niihara, Joan Oliva, Arjie Florentino, Amber Gorce, Jeremy Stark, Daileen Cortez, Samuel W. French, Yutaka Niihara. Proteasomes in corneal epithelial cells and cultured autologous oral mucosal epithelial cell sheet (CAOMECS) graft used for the ocular surface regeneration. The Ocular Surface. 2017 Oct; 15(4):749-758. doi: 10.1016/j.jtos.2017.05.010. Epub 2017 May 18. PMID: 28528957. 
  1. Fawzia Bardag-Gorce, Richard H. Hoft Andrew Wood, Joan Oliva, Hope Niihara, Andrew Makalinao, Jacquelyn Thropay, Derek Pan, Imara Meepe, Kumar Tiger, Julio Garcia, Amanda Laporte, Samuel W. French and Yutaka Niihara. The Role of E-Cadherin in Maintaining the Barrier Function of Corneal Epithelium after Treatment with Cultured Autologous Oral Mucosa Epithelial Cell Sheet Grafts for Limbal Stem Deficiency. J Ophthalmol. 2016:4805986. Epub 2016 Sep 29.  PMID: 27777792 http://www.hindawi.com/journals/joph/2016/4805986/ 
  1. Joan Oliva, Fawzia Bardag-Gorce, Andrew Wood, Sota H, Yutaka Niihara. Direct labeling of 19F-perfluorocarbon onto engineered multilayered cell sheet for MRI-based non-invasive cell tracking. Tissue Engineering and Regenerative Medicine (TERM). October 2015, Volume 12, Issue 5, pp 371-378. http://link.springer.com/article/10.1007/s13770-014-0092-x 
  1. Fawzia Bardag-Gorce, Joan Oliva, Andrew Wood, Richard H. Hoft, Derek Pan, Jacquelyn Thropay, Andrew Makalinao, Samuel W. French, Yutaka Niihara. Carrier-free cultured autologous oral mucosa epithelial cell sheet (CAOMECS) for corneal epithelium reconstruction: A histological study.  The Ocular Surface. 13(2), 150–163. 2015. DOI: 10.1016/j.jtos.2014.12.003. PMID: 25881998 https://www.ncbi.nlm.nih.gov/pubmed/25881998 
  1. Fawzia Bardag-Gorce, Joan Oliva, Andrew Wood, Hope Niihara, Andrew Makalinao, Sean Sabino, Derek Pan, Jacquelyn Thropay, Sota H, Yutaka Niihara. Microarray analysis of oral mucosal epithelial cell sheet.  Tissue Engineering and Regenerative Medicine.  2013;10(6):362-370.  http://link.springer.com/search?sortOrder=newestFirst&facet-content-type=Article&facet-journal-id=13770 

 

Abstracts 

  1. Atijah Collins, Kavita Narwani, Daileen Cortez, Lester L. Fulay, Will Hawkins, Darrell Cannon, Colonya Calhoun, Fawzia Bardag Gorce and Niihara Yutaka. Cell sheet technology for corneal surface reconstruction.  102nd Annual Meeting, San Antonio, Texas Oct. 5–10, 2020.  
  1. Kavita Narwani, Fawzia Bardag-Gorce, Christian Au, Jeremy Stark, Isaac Yang, Daileen Cortez, Alissa Diaz, Lester Lloyd L. Fulay and Yutaka Niihara. Effect of ECM substrates and cell culture surface on rabbits’ oral mucosal epithelial cells attachment and growth.  ISSCR annual meeting 2020 (24-27 June 2020, Boston, MA 02210).  
  1. Fawzia Bardag-Gorce, Kavita Narwani, Daileen Cortez, Isaac Yang, Jeremy Stark, Christian Au, Alissa Diaz, Yutaka Niihara.  Oral Mucosal Epithelial Cell Sheet for Clinical Application.  The Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, May 3-7, 2020 in Baltimore, MD.  Abstract Submission, ID: 3359230. 
  1. Joan Oliva, Fawzia Bardag-Gorce, Yutaka Niihara. Histone Phosphorylation Pattern In the Epithelium and CAOMECS. ISSCR annual meeting (Los Angeles, CA, 26-29 June 2019).  
  1. Valentina Sanghez, Michaelina Iacovino, Fawzia Bardag-Gorce, Yutaka Niihara, Joan Oliva. Characterization of the rabbit oral mucosal epithelial stem cells for CAOMECS engineering.  ISSCR annual meeting (Los Angeles, CA, 26-29 June 2019).  
  1. Fawzia Bardag-Gorce, Kavita Narwani, Daileen Cortez, Isaac Yang, Jeremy stark, Mynor Garcia, Alissa Diaz, Joan Oliva, Yutaka Niihara. Effects of Media Composition on the Phenotype of Oral Mucosal Epithelial Cell Sheet Cultured for Corneal Epithelium Reconstruction.  The Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, April 27 – May 2, 2019, in Vancouver, Canada. Abstract ID# 3138223.  
  1. Joan Oliva, Jun Ochiai, Fawzia Bardag-Gorce, Yutaka Niihara. Differentiation of vitrified stratified adipose-derived stem cell sheets.  Society of Cryobiology, July 22-25, 2019, San Diego, CA.  
  1. Fawzia Bardag-Gorce, Imara Meepe, Andrew Makalinao, Robert Niihara, Kavita Narwani, Richard Hoft, Alan Felsenfeld, Joan Oliva and Yutaka Niihara. Human Cultured Autologous Oral Mucosal Epithelial Cell Sheet (CAOMECS) and Progenitor Stem Cell Maintenance. ISSCR annual meeting (Melbourne, Australia, June 20-23, 2018).  Abstract ID # 445742.  
  1. Fawzia Bardag-Gorce, Richard Hoft, Derek Pan, Kavita Narwani, Michael Di Lorenzo, Daileen Cortez, Joan Oliva, and Yutaka Niihara. The Effect of Cultured Autologous Oral Mucosal Epithelial Cell Sheet (CAOMECS) Graft on Corneas with Experimental Limbal Stem Cell Deficiency and Neovascularization.  The Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, April 29 – May 4, 2018, in Hawaii. Abstract ID# 291967. 
  1. Fawzia Bardag-Gorce, Jeremy Stark, Richard Hoft, Kavita Narwani, Robert Niihara, Sarah Sunada, Daileen Cortez, Joan Oliva, and Yutaka Niihara. Expression of ALDH in Cultured Autologous Oral Mucosal Epithelial Cell Sheet (CAOMECS) Grafts for Ocular Surface Reconstruction.  Vision Science and Ophthalmology. Zurich, Switzerland, 2018.  
  1. Fawzia Bardag-Gorce, Amanda Laporte, Daileen Cortez, Robert Niihara, Sarah Sunada, Jeremy Stark, Amber Gorce, Richard H. Hoft, Julian Whitelegge, Joan Oliva, Samuel W. French, and Yutaka Niihara. Histidine Ammonia-Lyase is a Proteasome Interacting Protein. The American Society of Cell Biology Annual Meeting – Dec 2-6, 2017.  Philadelphia, USA. 
  1. Fawzia Bardag-Gorce, Joan Oliva, Andrew Wood, Hiroyuki Sota, Richard Hoft and Yutaka Niihara. Cultured Autologous Oral Mucosa Epithelial Cell Sheet (CAOMECS) For Corneal Epithelial Regeneration. Vision Science and Ophthalmology Thursday August 10, 2017, London, UK. http://visionscience.conferenceseries.com/scientific-program. 
  1. Fawzia Bardag-Gorce, Joan Oliva, Richard H. Hoft and Yutaka Niihara. The Ubiquitin Proteasome Pathway in Cultured Oral Mucosa Epithelial Cell Sheet (CAOMECS) for Ocular Surface Reconstruction.  Vision Science and Ophthalmology Friday August 11, 2017, London, UK. http://visionscience.conferenceseries.com/scientific-program. 
  1. Joan Oliva, Arjie Florentino, Yutaka Niihara. Long Term Storage of Vitrified CAOMECS Oral Mucosa Epithelial Cell Sheets. Society of Cryobiology, July 20-24, 2017, Hefei (China). 
  1. Fawzia Bardag-Gorce, Andrew Makalino, Richard Hoft, Amanda Laporte, Jeremy Stark, Imara Meepe, Joan Oliva, and Yutaka Niihara. Activation of proteasome by inhibiting autophagy in corneal epithelia cells with limbal stem cell deficiency.  The Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, May 7-11, 2017, in Baltimore, Maryland. Abstract ID# 2671427. 
  1. Fawzia Bardag-Gorce, Amanda Laporte, Julian Whitelegge and Yutaka Niihara. Proteasome activity modulation by targeting proteasome interacting proteins.  The American Society of Cell Biology Annual Meeting – Dec 3-7, 2016, San Francisco, CA. 
  1. Fawzia Bardag-Gorce, Amanda Laporte, Andrew Makalinao, Imara Meepe, Joan Oliva, Samuel W. French, Richard H. Hoft and Yutaka Niihara. Corneal keratins aggresome (CKAGG) formation and corneal epithelial cells opacification. XXII Biennial Meeting of the International Society for Eye Research – ISER. Tokyo, Japan Sep. 2016. Abstract # A-817-0003-00105. 
  1. Fawzia Bardag-Gorce, Joan Oliva, Andrew Makalinao, Imara Meepe, Julio Garcia, Amanda Laporte, Robert Niihara, Hyo Jung Ha, Richard H. Hoft; Alan Felsenfeld, and Yutaka Niihara. Barrier function of cultured autologous oral mucosal epithelial cell sheets. The Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, May 1 – 5, 2016. Seattle, Wash. Abstract # 2448515. 
  1. Imara Meepe, Joan Oliva, Amanda Laporte, Richard H. Hoft, Yutaka Niihara and Fawzia Bardag-Gorce. Proteasome activation for corneal epithelium proteins clearance after LSCD. The American Society of Cell Biology Annual Meeting, December 12 - 16, 2015. Mol. Biol. Cell (suppl), Abstract ID: 2018 (P1599--B1679). 
  1. Joan Oliva, Ken Ochiai, Andrew Wood, Fawzia Bardag-Gorce, Yutaka Niihara. Serum Free and Feeder Cells Free Oral Mucosa Epithelial Cell Sheet Engineering.  International Society for Stem Cell Research Annual Meeting (ISSCR) June 24 – 27, 2015.  Abstract #403- T-1470.  
  1. Fawzia Bardag-Gorce, Imara Meepe, Andrew Wood, Julio Garcia, Derek Pan, Joan Oliva, Richard Hoft and Yutaka Niihara. Proteasomes as a therapeutic target for abnormal rabbit corneal epithelium. The Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, May 3 – 7, 2015. Abstract # 5629-B0269. 
  1. Fawzia Bardag-Gorce, Imara Meepe, Andrew Wood, Julio Garcia, Derek Pan, Joan Oliva, Richard H. Hoft and Yutaka Niihara. Ubiquitin-Proteasome Pathway Activity in Cultured Oral Mucosal Epithelial Cell Sheet Grafts Used for Treatment of Experimental Limbal Stem Cell Deficiency in Rabbits. The American Society of Cell Biology Annual Meeting, December 6-10, 2014. Mol. Biol. Cell (suppl), Abstract No. 2377 (P770-B1077). 
  1. Fawzia Bardag-Gorce, Joan Oliva, Kumar Tiger, Andrew Wood, and Niihara, Yutaka. Muscle Derived Stem Cells Isolation and Characterization. International Society for Stem Cell Research (ISSCR) 12th Annual Meeting, June 18 - 21, 2014. Abstract # 902-F3049. 
  1. Fawzia Bardag-Gorce, Richard Hoft, Joan Oliva, Andrew Wood, Derek Pan, Jacquelyn Thropay, Andrew Makalinao, Hiroyuki Sota, Samuel W. French and Yutaka Niihara. Cultured Autologous Oral Mucosal Epithelial Cell Sheet Grafts for Treatment of Experimentally-induced Limbal Stem Cell Deficiency. The Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, May 4 – 8, 2014.  Abstract [5543, A0117]. 
  1. Andrew Wood, Hiroyuki Sota, Joan Oliva, Fawzia Bardag-Gorce, Yutaka Niihara. Autologous Cell Sheet Engineering: An Animal Product-Free Approach. Experimental Biology Annual Meeting. April 26-30, 2014. Abstract# 1180.23 (http://www.fasebj.org/content/28/1_Supplement/1180.23). 
  1. Fawzia Bardag-Gorce, Joan Oliva, Andrew Wood, Andrew Makalinao, Hope Niihara, Derek Pan, Jacquelyn Thropay, Hiroyuki Sota, Yutaka Niihara. Anti-Angiogenic Factors of Engineered Oral Mucosal Epithelial Cell Sheets for Corneal Regeneration. Experimental biology Annual Meeting, April 20-24, 2013. The FASEB Journal, 27:685.4. Abstract No. 685.4. http://www.fasebj.org/cgi/content/meeting_abstract/27/1_MeetingAbstracts/685.4. 
  1. Joan Oliva, Fawzia Bardag-Gorce, Richard Hoft, Andrew Wood, Derek Pan, Hiroyuki Sota, Yutaka Niihara. Limbal Stem Cell Deficiency Model in Rabbits for Experimental Corneal Surface Regeneration.  2013.  Experimental biology Annual Meeting. The FASEB Journal, 27:751.2.  Abstract No. 751.2. (http://www.fasebj.org/cgi/content/meeting_abstract/27/1_MeetingAbstracts/751.2). 
  1. Joan Oliva, Fawzia Bardag-Gorce, Andrew Wood, Amy Wesa, Brooke Helfer, Anthony Balducci, Hiroyuki Sota, Yutaka Niihara. Direct labeling of 19F-perfluorocarbon onto engineered multilayered cell sheet for MRI-based non-invasive cell tracking. 2012. The American Society of Cell Biology Annual Meeting. Mol. Biol. Cell (suppl), Abstract No. 2518. 
  1. Fawzia Bardag-Gorce, Andrew Wood, Joan Oliva, Hope Niihara, Andrew Makalinao, Hiroyuki Sota, Yutaka Niihara Y. Adhesion Molecules in Cell Sheet Engineering for Corneal Epithelium Regeneration. The American Society of Cell Biology Annual Meeting December 15-19, 2012. Mol. Biol Cell (suppl), Abstract No. 1333.   
  1. Joan Oliva, Andrew Wood, Hiroyuki Sota, Yutaka Niihara and Fawzia Bardag-Gorce. Molecular Analysis of Cultured Oral Mucosal Epithelial Cell Sheet for Corneal Regeneration. International Society for Stem Cell Research 10th Annual Meeting, June 13 - 16, 2012.  Abstract No. 1855.  
  1. Fawzia Bardag-Gorce, Joan Oliva, Andrew Wood, Hope Niihara, Sota Hiroyuki, Yutaka Niihara. Microarray Analysis of Epithelial Cell Sheets (ECS) Expanded Ex Vivo from Oral Mucosa for Corneal Regeneration. 2012. International Society for Stem Cell Research 10th Annual Meeting, June 13 - 16, 2012.  Abstract No. 1859.
  2. Hung Lam, Joseph M Becerra, Charles W Stark, Yutaka Niihara and Michael Callaghan. The Evaluation of Transfusion Data from the Phase 3 Clinical Study of L-Glutamine in Sickle Cell Disease. 2021. 63rd American Society of Hematology (ASH) Annual Meeting and Exhibition. https://doi.org/10.1182/blood-2021-154477
  3. Narcisse Elenga, Maryse Etienne-Julan, Gylna Loko, Randa AlOkka, Ahmad Adel, Mohamed Yassin. Real World Data on Efficacy of Pharmaceutical-Grade L-Glutamine in Preventing Sickle Cell Disease-Related Acute Complications and Hemolysis in Pediatric and Adult Patients. 2021. 62nd Annual Meeting of the British Society for Haematology (BSH). E-poster No. BSH22- EP78.